Methylation Mutation Resources

At MyPassion4Health we frequently test for methylation mutations, which can be a fundamental root of illness.  Explaining what the mutation is and the many and diverse illnesses associated with methylation mutations in an hour appointment is close to impossible.  Therefore we are offering this blog piece as a resource guide for those who want to better understand what they have and why it is so important to treat.

Good Overviews:

The famous diagram everyone gets shown:

How this all relates to epigenetics, which is the science of how environment can influence our genes:

Ethnic distribution of C677T allele (highest in Mexicans and Italians):

Association of Methylation Mutations with Autism:

Why BH4 is so important for the A1298C mutation:

More Links:

A really fun song that makes all the science a little more interesting:

Mary Ackerley MD, MD(H), ABIHM is a classically trained psychiatrist and homeopathic physician who specializes in the holistic treatment of depression, anxiety, bipolar disorders, digestive disturbances and hormone replacement therapy.

She can be reached through her clinic MyPassion4Health at 520-299-5694 or online at

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